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Cardiovascular safety data from published trials showed reductions in systolic blood pressure (ranging from 4.3 to 7.9 mmHg depending on dose) and diastolic blood pressure (2.3 to 4.6 mmHg reductions)
The company highlights its use of the arginate salt form, which it describes as offering greater gastrointestinal stability for oral delivery compared to acetate-form products
Evidence includes: Stimulation of endothelial and keratinocyte migration Enhanced blood vessel density in wound healing models Promotion of stem cell differentiation toward repair cell lineages Low molecular weight enabling tissue penetration over long distances Unlike growth factors that bind to extracellular matrix, TB-500s mobility allows systemic distribution to multiple injury sites
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